Basel Institute for Clinical Epidemiology and Biostatistics (ceb)

Research Focus:

The research focus of the institute is evidence synthesis, Health Technology Assessment, methodology research in clinical epidemiology, and data analysis of large scale observational data.

Cooperation and Networking:

CEB has national collaborations with the Swiss HIV Cohort Study and the Swiss Transplant Cohort Study. CEB collaborates with and participates in the European HIV Network Eurocoord, the Swiss Network for Health Technology Assessment (SNHTA), European Network for Health Technology Assessment (EUnetHTA), the Translational Research on Antimicrobial resistance and community-acquired infections in Europe network (TRACE), The Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group, and the Evidence based Medicine Working group and the REporting of studies Conducted using Observational Routinely-collected Data (RECORD) collaboration.

CEB has continuous international collaborations with German Cochrane Center Freiburg i. Br., University College London (UCL) UK, Erasmus University Rotterdam NL, McMaster University, Hamilton Canada, Stanford University, USA, and Primary Care and Population Sciences Academic Unit, University of Southampton UK. CEB has national collaborations with the Institutes of Social and Preventive Medicine of the Universities of Bern, Lausanne and Zurich.


Publications (full publication record:

  • Koller MT, Leening MJ, Wolbers M, Steyerberg EW, Hunink MG, Schoop R, Hofman A, Bucher HC, Psaty BM, Lloyd-Jones DM, Witteman JC. Development and validation of a coronary risk prediction model for older U.S. and European persons in the cardiovascular health study and the Rotterdam Study Ann Intern Med ; September 18, 2012 ; 157 (6) : 389-397.
  • Schuetz P, Briel M, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Luyt CE, Chastre J, Tubach F, Kristoffersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Mueller B Procalcitonin to Guide Initiation and Duration of Antibiotic Treatment in Acute Respiratory Infections: An Individual Patient Data Meta-Analysis Clin Infect Dis; September 1, 2012 ; 55 (5) : 651-662.
  • Young J, Psichogiou M, Meyer L, Ayayi S, Grabar S, Raffi F, Reiss P, Gazzard B, Sharland M, Gutierrez F, Obel N, Kirk O, Miro JM, Furrer H, Castagna A, De Wit S, Mu … Bucher HC for COHERE in Eurocoord. CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE PLoS Med , 2012 ; 9 (3) : e1001194-1-e1001194-9.
  • Gloy VL, Briel M, Bhatt DL, Kashyap SR, Schauer PR, Mingrone G, Bucher HC, Nordmann AJ: Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials BMJ ; October 22, 2013 ; 347 : f5934-.
  • Kasenda B., von Elm E., You J., Blumle A., Tomonaga Y., Saccilotto R., Amstutz A., Bengough T., Meerpohl J.J., Stegert M., Tikkinen K.A., Neumann I., Carrasco-Labra A., Faulhaber M., Mulla S.M., Mertz D., Akl E.A., Bassler D., Busse J.W., Ferreira-Gonzalez I., Lamontagne F., Nordmann A., Gloy V., Raatz H., Moja L., Rosenthal R., Ebrahim S., Schandelmaier S., Xin S., Vandvik P.O., Johnston B.C., Walter M.A., Burnand B., Schwenkglenks M., Hemkens L.G., Bucher H.C., Guyatt G.H., Briel M. Prevalence, characteristics, and publication of discontinued randomized trials JAMA 2014; 311: 1045-51.
  • Siemieniuk R. A., Meade M. O., Alonso-Coello P., Briel M., Evaniew N., Prasad M., Alexander P. E., Fei Y., Vandvik P. O., Loeb M., Guyatt G. H. Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis. Ann Intern Med 2015; 163(7): 519-528.
  • Amato M. B., Meade M. O., Slutsky A. S., Brochard L., Costa E. L., Schoenfeld D. A., Stewart T. E., Briel M., Talmor D., Mercat A., Richard J. C., Carvalho C. R., Brower R. G. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 2015; 372(8): 747-755.